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Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods

BACKGROUND: We investigated the influence of genotyping errors on the type I error rate and empirical power of two haplotype based association methods applied to candidate regions. We compared the performance of the Mantel Statistic Using Haplotype Sharing and the haplotype frequency based score tes...

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Detaylı Bibliyografya
Asıl Yazarlar: Marquard, Vivien, Beckmann, Lars, Heid, Iris M, Lamina, Claudia, Chang-Claude, Jenny
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648998/
https://ncbi.nlm.nih.gov/pubmed/19178712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-3
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