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Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods

BACKGROUND: We investigated the influence of genotyping errors on the type I error rate and empirical power of two haplotype based association methods applied to candidate regions. We compared the performance of the Mantel Statistic Using Haplotype Sharing and the haplotype frequency based score tes...

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Main Authors: Marquard, Vivien, Beckmann, Lars, Heid, Iris M, Lamina, Claudia, Chang-Claude, Jenny
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648998/
https://ncbi.nlm.nih.gov/pubmed/19178712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-10-3
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