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Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders
Genomic disorders are a clinically diverse group of conditions caused by gain, loss or re-orientation of a genomic region containing dosage-sensitive genes. One class of genomic disorder is caused by hemizygous deletions resulting in haploinsufficiency of a single or, more usually, several genes. Fo...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers Ltd.
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679649/ https://ncbi.nlm.nih.gov/pubmed/19440510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920208784340795 |
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