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Insight into the Structural Basis of Pro- and Antiapoptotic p53 Modulation by ASPP Proteins

p53-dependent apoptosis is modulated by the ASPP family of proteins (apoptosis-stimulating proteins of p53; also called ankyrin repeat-, Src homology 3 domain-, and Pro-rich region-containing proteins). Its three known members, ASPP1, ASPP2, and iASPP, were previously found to interact with p53, inf...

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Autors principals: Ahn, Jinwoo, Byeon, In-Ja L., Byeon, Chang-Hyeock, Gronenborn, Angela M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679482/
https://ncbi.nlm.nih.gov/pubmed/19246451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808821200
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