TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

The TAZ transcription co-activator has been shown to promote cell proliferation and to induce epithelial-mesenchymal transition. Recently we have demonstrated that TAZ is phosphorylated and inhibited by the Hippo tumor suppressor pathway, which is altered in human cancer. The mechanism of TAZ-mediat...

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Main Authors: Zhang, Heng, Liu, Chen-Ying, Zha, Zheng-Yu, Zhao, Bin, Yao, Jun, Zhao, Shimin, Xiong, Yue, Lei, Qun-Ying, Guan, Kun-Liang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679435/
https://ncbi.nlm.nih.gov/pubmed/19324877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900843200
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