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Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells
Nicotinamide at millimolar concentrations affects cell survival in various conditions, and is being utilized therapeutically in many human diseases. However, the effect of an acute treatment of nicotinamide at such high dose on gene expression and cellular metabolism has rarely been determined previ...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Society of Medical Biochemistry and Molecular Biology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679301/ https://ncbi.nlm.nih.gov/pubmed/18446063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.2.246 |
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