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CD98 activation increases surface expression and clustering of β(1) integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms

CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates β(1) integrin-mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of β(1) integrin are presently unclear. In this study, the effects of CD98 signaling on the express...

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Detalles Bibliográficos
Main Authors: Kim, Sun-Mi, Hahn, Jang-Hee
Formato: Artigo
Idioma:Inglês
Publicado: Korean Society of Medical Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679289/
https://ncbi.nlm.nih.gov/pubmed/18587263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.3.261
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