Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

Integrin adhesion complexes (IACs) form mechanochemical connections between the extracellular matrix and actin cytoskeleton and mediate phenotypic responses via posttranslational modifications. Here, we investigate the modularity and robustness of the IAC network to pharmacological perturbation of t...

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Vydáno v:J Cell Biol
Hlavní autoři: Horton, Edward R., Humphries, Jonathan D., Stutchbury, Ben, Jacquemet, Guillaume, Ballestrem, Christoph, Barry, Simon T., Humphries, Martin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739608/
https://ncbi.nlm.nih.gov/pubmed/26833789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508080
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