Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition

Integrin adhesion complexes (IACs) form mechanochemical connections between the extracellular matrix and actin cytoskeleton and mediate phenotypic responses via posttranslational modifications. Here, we investigate the modularity and robustness of the IAC network to pharmacological perturbation of t...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Horton, Edward R., Humphries, Jonathan D., Stutchbury, Ben, Jacquemet, Guillaume, Ballestrem, Christoph, Barry, Simon T., Humphries, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739608/
https://ncbi.nlm.nih.gov/pubmed/26833789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508080
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