The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis

BACKGROUND: Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that plays an important role in survival signaling. FAK has been shown to be overexpressed in breast cancer tumors at early stages of tumorigenesis. METHODS: To study the direct effect of FAK on breast tumorigenesis, we develo...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Golubovskaya, Vita M, Zheng, Min, Zhang, Li, Li, Jian-Liang, Cance, William G
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087335/
https://ncbi.nlm.nih.gov/pubmed/19671193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-280
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