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Estrogen Receptor β-Mediated Nuclear Interaction Between IRS-1 and Rad51 Inhibits Homologous Recombination Directed DNA Repair in Medulloblastoma
In medulloblastomas, which are highly malignant cerebellar tumors of the childhood genotoxic treatments such as cisplatin or γ-irradiation are frequently associated with DNA damage, which often associates with unfaithful DNA repair, selection of new adaptations and possibly tumor recurrences. Theref...
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| Autores principales: | , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679153/ https://ncbi.nlm.nih.gov/pubmed/19117011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21683 |
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