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Acetylation of PAMAM dendrimers for cellular delivery of siRNA

BACKGROUND: The advancement of gene silencing via RNA interference is limited by the lack of effective short interfering RNA (siRNA) delivery vectors. Rational design of polymeric carriers has been complicated by the fact that most chemical modifications affect multiple aspects of the delivery proce...

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Detalles Bibliográficos
Main Authors: Waite, Carolyn L, Sparks, Sarah M, Uhrich, Kathryn E, Roth, Charles M
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679008/
https://ncbi.nlm.nih.gov/pubmed/19389227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-38
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