Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4

BACKGROUND: Neutrophils play an important role in the pathophysiology of RSV, though RSV does not appear to directly activate neutrophils in the lower airways. Therefore locally produced cytokines or other molecules released by virally-infected airway epithelial cells are likely responsible for recr...

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Bibliografski detalji
Glavni autori: Wheeler, Derek S, Chase, Margaret A, Senft, Albert P, Poynter, Sue E, Wong, Hector R, Page, Kristen
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679007/
https://ncbi.nlm.nih.gov/pubmed/19405961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-31
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