Extracellular Hsp72, an endogenous DAMP, is released by virally infected airway epithelial cells and activates neutrophils via Toll-like receptor (TLR)-4

BACKGROUND: Neutrophils play an important role in the pathophysiology of RSV, though RSV does not appear to directly activate neutrophils in the lower airways. Therefore locally produced cytokines or other molecules released by virally-infected airway epithelial cells are likely responsible for recr...

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Hlavní autoři: Wheeler, Derek S, Chase, Margaret A, Senft, Albert P, Poynter, Sue E, Wong, Hector R, Page, Kristen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679007/
https://ncbi.nlm.nih.gov/pubmed/19405961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-31
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