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Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists

Atherosclerosis is a chronic inflammatory vascular disease. Toll-like receptors (TLRs) are major initiators of inflammation. TLR2 promotes atherosclerosis in LDL receptor (LDLr)-deficient mice fed a high-fat diet (HFD). TLR2 forms heterodimers with TLR1 or TLR6 to enable inflammatory responses in th...

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Détails bibliographiques
Auteurs principaux: Curtiss, Linda K., Black, Audrey S., Bonnet, David J., Tobias, Peter S.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435545/
https://ncbi.nlm.nih.gov/pubmed/22822027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M028431
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