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Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration

Glial-derived neurotrophic factor (GDNF) promotes both sensory and motor neuron survival. The delivery of GDNF to the peripheral nervous system has been shown to enhance regeneration following injury. In this study we evaluated the effect of affinity-based delivery of GDNF from a fibrin matrix in a...

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Библиографические подробности
Главные авторы: Wood, Matthew D., Moore, Amy M., Hunter, Daniel A., Tuffaha, Sami, Borschel, Gregory H., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678870/
https://ncbi.nlm.nih.gov/pubmed/19103514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2008.11.008
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