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Finely Tuned Temporal and Spatial Delivery of GDNF Promotes Enhanced Nerve Regeneration in a Long Nerve Defect Model

The use of growth factors, such as glial cell line-derived neurotrophic factor (GDNF), for the treatment of peripheral nerve injury has been useful in promoting axon survival and regeneration. Unfortunately, finding a method that delivers the appropriate spatial and temporal release profile to promo...

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Bibliographic Details
Published in:Tissue Eng Part A
Main Authors: Marquardt, Laura M., Ee, Xueping, Iyer, Nisha, Hunter, Daniel, Mackinnon, Susan E., Wood, Matthew D., Sakiyama-Elbert, Shelly E.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684669/
https://ncbi.nlm.nih.gov/pubmed/26466815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2015.0311
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