Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

BACKGROUND: The advent of targeted therapies in hepatocellular carcinoma (HCC) has underscored the importance of pathway characterization to identify novel molecular targets for treatment. Based on its role in cell growth and differentiation, we evaluated mTOR signaling activation in human HCC, as w...

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Detalhes bibliográficos
Main Authors: Villanueva, Augusto, Chiang, Derek Y., Newell, Pippa, Peix, Judit, Thung, Swan, Alsinet, Clara, Tovar, Victoria, Roayaie, Sasan, Minguez, Beatriz, Sole, Manel, Battiston, Carlo, van Laarhoven, Stijn, Fiel, Maria I, Di Feo, Analisa, Hoshida, Yujin, Yea, Steven, Toffanin, Sara, Ramos, Alex, Martignetti, John A., Mazzaferro, Vincenzo, Bruix, Jordi, Waxman, Samuel, Schwartz, Myron, Meyerson, Matthew, Friedman, Scott L., Llovet, Josep M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678688/
https://ncbi.nlm.nih.gov/pubmed/18929564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.08.008
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