Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

BACKGROUND: The advent of targeted therapies in hepatocellular carcinoma (HCC) has underscored the importance of pathway characterization to identify novel molecular targets for treatment. Based on its role in cell growth and differentiation, we evaluated mTOR signaling activation in human HCC, as w...

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Main Authors: Villanueva, Augusto, Chiang, Derek Y., Newell, Pippa, Peix, Judit, Thung, Swan, Alsinet, Clara, Tovar, Victoria, Roayaie, Sasan, Minguez, Beatriz, Sole, Manel, Battiston, Carlo, van Laarhoven, Stijn, Fiel, Maria I, Di Feo, Analisa, Hoshida, Yujin, Yea, Steven, Toffanin, Sara, Ramos, Alex, Martignetti, John A., Mazzaferro, Vincenzo, Bruix, Jordi, Waxman, Samuel, Schwartz, Myron, Meyerson, Matthew, Friedman, Scott L., Llovet, Josep M.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678688/
https://ncbi.nlm.nih.gov/pubmed/18929564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.08.008
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