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Distinct patterns of brain activity in young carriers of the APOE-ε4 allele

The APOE ε4 allele is a risk factor for late-life pathological changes that is also associated with anatomical and functional brain changes in middle-aged and elderly healthy subjects. We investigated structural and functional effects of the APOE polymorphism in 18 young healthy APOE ε4-carriers and...

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Bibliographische Detailangaben
Hauptverfasser: Filippini, Nicola, MacIntosh, Bradley J., Hough, Morgan G., Goodwin, Guy M., Frisoni, Giovanni B., Smith, Stephen M., Matthews, Paul M., Beckmann, Christian F., Mackay, Clare E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678478/
https://ncbi.nlm.nih.gov/pubmed/19357304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811879106
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