Oxytocin is an anabolic bone hormone

We report that oxytocin (OT), a primitive neurohypophyseal hormone, hitherto thought solely to modulate lactation and social bonding, is a direct regulator of bone mass. Deletion of OT or the OT receptor (Oxtr) in male or female mice causes osteoporosis resulting from reduced bone formation. Consist...

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Detalhes bibliográficos
Main Authors: Tamma, Roberto, Colaianni, Graziana, Zhu, Ling-ling, DiBenedetto, Adriana, Greco, Giovanni, Montemurro, Gabriella, Patano, Nicola, Strippoli, Maurizio, Vergari, Rosaria, Mancini, Lucia, Colucci, Silvia, Grano, Maria, Faccio, Roberta, Liu, Xuan, Li, Jianhua, Usmani, Sabah, Bachar, Marilyn, Bab, Itai, Nishimori, Katsuhiko, Young, Larry J., Buettner, Christoph, Iqbal, Jameel, Sun, Li, Zaidi, Mone, Zallone, Alberta
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678458/
https://ncbi.nlm.nih.gov/pubmed/19369205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901890106
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