Osteoblast regulation via ligand-activated nuclear trafficking of the oxytocin receptor

We report that oxytocin (Oxt) receptors (Oxtrs), on stimulation by the ligand Oxt, translocate into the nucleus of osteoblasts, implicating this process in the action of Oxt on osteoblast maturation. Sequential immunocytochemistry of intact cells or isolated nucleoplasts stripped of the outer nuclea...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Di Benedetto, Adriana, Sun, Li, Zambonin, Carlo G., Tamma, Roberto, Nico, Beatrice, Calvano, Cosima D., Colaianni, Graziana, Ji, Yaoting, Mori, Giorgio, Grano, Maria, Lu, Ping, Colucci, Silvia, Yuen, Tony, New, Maria I., Zallone, Alberta, Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246276/
https://ncbi.nlm.nih.gov/pubmed/25378700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419349111
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