Bone Marrow Oxytocin Mediates the Anabolic Action of Estrogen on the Skeleton

Estrogen uses two mechanisms to exert its effect on the skeleton: it inhibits bone resorption by osteoclasts and, at higher doses, can stimulate bone formation. Although the antiresorptive action of estrogen arises from the inhibition of the MAPK JNK, the mechanism of its effect on the osteoblast re...

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Detalhes bibliográficos
Main Authors: Colaianni, Graziana, Sun, Li, Di Benedetto, Adriana, Tamma, Roberto, Zhu, Ling-Ling, Cao, Jay, Grano, Maria, Yuen, Tony, Colucci, Sylvia, Cuscito, Concetta, Mancini, Lucia, Li, Jianhua, Nishimori, Katsuhiko, Bab, Itai, Lee, Heon-Jin, Iqbal, Jameel, Young, W. Scott, Rosen, Clifford, Zallone, Alberta, Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436530/
https://ncbi.nlm.nih.gov/pubmed/22761429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365049
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