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Regulation of different inflammatory diseases by impacting the mevalonate pathway

The 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) interfere with the mevalonate pathway. While initially developed for their lipid-lowering properties, statins have been extensively investigated with respect to their impact on autoantigen and alloantigen driven immune respons...

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Main Authors: Zeiser, Robert, Maas, Kristina, Youssef, Sawsan, Dürr, Christoph, Steinman, Lawrence, Negrin, Robert S
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678178/
https://ncbi.nlm.nih.gov/pubmed/19191903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03011.x
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