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Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function

BACKGROUND: Transgenic chloroplasts are potential bioreactors for recombinant protein production, especially for achievement of high levels of protein expression and proper folding. Production of therapeutic proteins in leaves provides transgene containment by elimination of reproductive structures....

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Detalhes bibliográficos
Main Authors: Daniell, Henry, Ruiz, Gricel, Denes, Bela, Sandberg, Laurence, Langridge, William
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678116/
https://ncbi.nlm.nih.gov/pubmed/19344517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-33
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