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Codon Optimization to Enhance Expression Yields Insights into Chloroplast Translation
Codon optimization based on psbA genes from 133 plant species eliminated 105 (human clotting factor VIII heavy chain [FVIII HC]) and 59 (polio VIRAL CAPSID PROTEIN1 [VP1]) rare codons; replacement with only the most highly preferred codons decreased transgene expression (77- to 111-fold) when compar...
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| Pubblicato in: | Plant Physiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Plant Biologists
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5074611/ https://ncbi.nlm.nih.gov/pubmed/27465114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.16.00981 |
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