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Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide

Current treatment for type I diabetes includes delivery of insulin via injection or pump, which is highly invasive and expensive. The production of chloroplast-derived proinsulin should reduce cost and facilitate oral delivery. Therefore, tobacco and lettuce chloroplasts were transformed with the ch...

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Autori principali: Boyhan, Diane, Daniell, Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480330/
https://ncbi.nlm.nih.gov/pubmed/21143365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1467-7652.2010.00582.x
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