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Island method for estimating the statistical significance of profile-profile alignment scores
BACKGROUND: In the last decade, a significant improvement in detecting remote similarity between protein sequences has been made by utilizing alignment profiles in place of amino-acid strings. Unfortunately, no analytical theory is available for estimating the significance of a gapped alignment of t...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678096/ https://ncbi.nlm.nih.gov/pubmed/19379500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-112 |
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