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Island method for estimating the statistical significance of profile-profile alignment scores

BACKGROUND: In the last decade, a significant improvement in detecting remote similarity between protein sequences has been made by utilizing alignment profiles in place of amino-acid strings. Unfortunately, no analytical theory is available for estimating the significance of a gapped alignment of t...

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Sonraí Bibleagrafaíochta
Príomhúdar: Poleksic, Aleksandar
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678096/
https://ncbi.nlm.nih.gov/pubmed/19379500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-112
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