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Termination of Cardiac Ca(2+) Sparks: Role of Intra-SR [Ca(2+)], Release Flux, and Intra-SR Ca(2+) Diffusion
Ca(2+) release from cardiac sarcoplasmic reticulum (SR) via ryanodine receptors (RyRs) is regulated by dyadic cleft [Ca(2+)] and intra-SR free [Ca(2+)] ([Ca(2+)](SR)). Robust SR Ca(2+) release termination is important for stable excitation–contraction coupling, and partial [Ca(2+)](SR) depletion may...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678058/ https://ncbi.nlm.nih.gov/pubmed/18787194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.183236 |
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