How β-Lactam Antibiotics Enter Bacteria: A Dialogue with the Porins

BACKGROUND: Multi-drug resistant (MDR) infections have become a major concern in hospitals worldwide. This study investigates membrane translocation, which is the first step required for drug action on internal bacterial targets. β-lactams, a major antibiotic class, use porins to pass through the ou...

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Main Authors: James, Chloë E., Mahendran, Kozhinjampara R., Molitor, Alexander, Bolla, Jean-Michel, Bessonov, Andrey N., Winterhalter, Mathias, Pagès, Jean-Marie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677626/
https://ncbi.nlm.nih.gov/pubmed/19434239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005453
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