Interplay Between Cytosolic Dopamine, Calcium and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

The basis for selective death of specific neuronal populations in neurodegenerative diseases remains unclear. Parkinson's disease (PD) is a synucleinopathy characterized by a preferential loss of dopaminergic neurons in the substantia nigra (SN), whereas neurons of the ventral tegmental area (V...

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Autores principales: Mosharov, Eugene V., Larsen, Kristin E., Kanter, Ellen, Phillips, Kester A., Wilson, Krystal, Schmitz, Yvonne, Krantz, David E., Kobayashi, Kazuto, Edwards, Robert H., Sulzer, David
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677560/
https://ncbi.nlm.nih.gov/pubmed/19409267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.01.033
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