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PLAQUE-BEARING MICE WITH REDUCED LEVELS OF OLIGOMERIC AMYLOID-β ASSEMBLIES HAVE INTACT MEMORY FUNCTION

The amyloid-β (Aβ) protein exists in the aging mammalian brain in diverse assembly states, including amyloid plaques and soluble Aβ oligomers. Both forms of Aβ have been shown to impair neuronal function, but their precise roles in Alzheimer’s disease (AD)-associated memory loss remain unclear. Both...

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Detaylı Bibliyografya
Asıl Yazarlar: Lesné, Sylvain, Kotilinek, Linda, Ashe, Karen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677385/
https://ncbi.nlm.nih.gov/pubmed/18155846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.10.054
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