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Demonstration of a Peroxide Shunt in the Tetrahydropterin-Dependent Aromatic Amino Acid Monooxygenases

The non-heme iron enzyme phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylase catalyze the hydroxylation of their aromatic amino acid substrates using a tetrahydropterin as the source of electrons. The hydroxylating intermediate is proposed to be an Fe(IV)O species. We report...

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Sonraí Bibleagrafaíochta
Main Authors: Pavon, Jorge Alex, Fitzpatrick, Paul F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676924/
https://ncbi.nlm.nih.gov/pubmed/19281164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja900128m
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