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The Effect of Methionine Oxidation on Structural Properties, Conformational Stability, and Aggregation of Immunoglobulin Light Chain LEN

Light chain amyloidoses arise from the overproduction and abnormal deposition of immunoglobulin light chain in various organs. LEN is the variable domain of an immunoglobulin light chain originally isolated from the urine of a patient suffering from multiple myeloma, with no sign of renal dysfunctio...

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Bibliografiske detaljer
Main Authors: Hu, Dongmei, Qin, Zhijie, Xue, Bin, Fink, Anthony L., Uversky, Vladimir N.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676884/
https://ncbi.nlm.nih.gov/pubmed/18652490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800806d
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