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The Effect of Methionine Oxidation on Structural Properties, Conformational Stability, and Aggregation of Immunoglobulin Light Chain LEN

Light chain amyloidoses arise from the overproduction and abnormal deposition of immunoglobulin light chain in various organs. LEN is the variable domain of an immunoglobulin light chain originally isolated from the urine of a patient suffering from multiple myeloma, with no sign of renal dysfunctio...

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Detalhes bibliográficos
Main Authors: Hu, Dongmei, Qin, Zhijie, Xue, Bin, Fink, Anthony L., Uversky, Vladimir N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676884/
https://ncbi.nlm.nih.gov/pubmed/18652490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800806d
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