Llwytho...

LKB1: cancer, polarity, metabolism, and now fertility

The LKB1 serine/threonine kinase is a tumor suppressor responsible for the inherited familial cancer disorder Peutz-Jeghers syndrome and is inactivated in a large percentage of human lung cancers. LKB1 acts a master kinase, directly phosphorylating and activating a family of 14 AMPK-related kinases...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: SHAW, Reuben J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676712/
https://ncbi.nlm.nih.gov/pubmed/18939946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082023
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