Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras

During B cell development, rearrangement and expression of Ig heavy chain (HC) genes promote development and expansion of pre-B cells accompanied by the onset of Ig light chain (LC) variable region gene assembly. To elucidate the signaling pathways that control these events, we have tested the abili...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Shaw, Albert C., Swat, Wojciech, Davidson, Laurie, Alt, Frederick W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2239
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