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In situ detection of activated Bruton’s tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies
Bruton’s tyrosine kinase (Btk) is a critical transducer of signals originating from the B cell antigen receptor (BCR). Dosage, sequential phosphorylation, and protein interactions are interdependent mechanisms influencing Btk function. Phosphopeptide-specific mAbs recognizing two distinct phosphotyr...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The National Academy of Sciences
1999
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC26764/ https://ncbi.nlm.nih.gov/pubmed/10051622 |
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