Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells

Mutation of Bruton's tyrosine kinase (Btk) causes human X-linked agammaglobulinemia and murine X-linked immunodeficiency syndrome (xid). Quantitative aspects of B lymphocyte development and function have been demonstrated to depend on Btk level in vivo by using a murine transgenic model system....

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Main Authors: Nisitani, Sazuku, Satterthwaite, Anne B., Akashi, Koichi, Weissman, Irving L., Witte, Owen N., Wahl, Matthew I.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC15999/
https://ncbi.nlm.nih.gov/pubmed/10688914
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