Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells

Mutation of Bruton's tyrosine kinase (Btk) causes human X-linked agammaglobulinemia and murine X-linked immunodeficiency syndrome (xid). Quantitative aspects of B lymphocyte development and function have been demonstrated to depend on Btk level in vivo by using a murine transgenic model system. A se...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nisitani, Sazuku, Satterthwaite, Anne B., Akashi, Koichi, Weissman, Irving L., Witte, Owen N., Wahl, Matthew I.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050583597
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