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A novel transcript of the LMO2 gene, LMO2-c, is regulated by GATA-1 and PU.1 and encodes an antagonist of LMO2

Ectopic expression of LIM-only protein 2 (LMO2) in T-cells, as a result of chromosomal translocations or retroviral insertion, plays an important role in the onset of T-cell leukemias. Two transcripts of LMO2 gene (LMO2-a and LMO2-b) have been reported to encode a same 158-amino-acid protein. We hav...

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Bibliografske podrobnosti
Main Authors: Wang, Q, Zhang, M, Wang, X, Yuan, W, Chen, D, Royer-Pokora, B, Zhu, T
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676384/
https://ncbi.nlm.nih.gov/pubmed/17361224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.leu.2404644
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