Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1

The control of red blood cell and megakaryocyte development by the regulatory protein GATA1 is a paradigm for transcriptional regulation of gene expression in cell lineage differentiation and maturation. Most GATA1-regulated events require GATA1 to bind FOG1, and essentially all GATA1-activated gene...

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Main Authors: Wilkinson-White, Lorna, Gamsjaeger, Roland, Dastmalchi, Siavoush, Wienert, Beeke, Stokes, Philippa H., Crossley, Merlin, Mackay, Joel P., Matthews, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167507/
https://ncbi.nlm.nih.gov/pubmed/21844373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105898108
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