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EXOGENOUS MANNOSE DOES NOT RAISE STEADY STATE MANNOSE-6-PHOSPHATE POOLS OF NORMAL OR N-GLYCOSYLATION-DEFICIENT HUMAN FIBROBLASTS
Increasing intracellular mannose-6-phosphate (Man-6-P) was previously reported to reduce the amount of the major lipid linked oligosaccharide (LLO) precursor of N-glycans; a loss that might decrease cellular N-glycosylation. If so, providing dietary mannose supplements to glycosylation-deficient pat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676341/ https://ncbi.nlm.nih.gov/pubmed/19157945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2008.12.005 |
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