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Mannose corrects altered N-glycosylation in carbohydrate-deficient glycoprotein syndrome fibroblasts.

Type I carbohydrate-deficient glycoprotein syndrome (CDGS) patients fail to add entire N-linked oligosaccharide chains to some serum glycoproteins. Here we show that four CDGS fibroblast cell lines have two related glycosylation abnormalities. First, they incorporate 3-10-fold less [3H] mannose into...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Panneerselvam, K, Freeze, H H
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617881/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118570
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