Caveolin-1–dependent apoptosis induced by fibrin degradation products

In mice lacking the blood coagulation regulator thrombomodulin, fibrinolytic degradation products (FDP) of fibrin induce apoptotic cell death of a specialized cell type in the placenta, polyploid trophoblast giant cells. Here, we document that this bioactivity of FDP is conserved in human FDP, is no...

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Detalhes bibliográficos
Main Authors: Guo, Yi-He, Hernandez, Irene, Isermann, Berend, Kang, Tae-bong, Medved, Leonid, Sood, Rashmi, Kerschen, Edward J., Holyst, Trudy, Mosesson, Michael W., Weiler, Hartmut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676096/
https://ncbi.nlm.nih.gov/pubmed/19074731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169433
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