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Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin
Absence of the blood coagulation inhibitor thrombomodulin (Thbd) from trophoblast cells of the mouse placenta causes a fatal arrest of placental morphogenesis. The pathogenesis of placental failure requires tissue factor, yet is not associated with increased thrombosis and persists in the absence of...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481555/ https://ncbi.nlm.nih.gov/pubmed/18490515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111302 |
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