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Maternal Par4 and platelets contribute to defective placenta formation in mouse embryos lacking thrombomodulin

Absence of the blood coagulation inhibitor thrombomodulin (Thbd) from trophoblast cells of the mouse placenta causes a fatal arrest of placental morphogenesis. The pathogenesis of placental failure requires tissue factor, yet is not associated with increased thrombosis and persists in the absence of...

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Auteurs principaux: Sood, Rashmi, Sholl, Lynette, Isermann, Berend, Zogg, Mark, Coughlin, Shaun R., Weiler, Hartmut
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481555/
https://ncbi.nlm.nih.gov/pubmed/18490515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-111302
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