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Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors

As a continuation of efforts to replace the metabolically labile methyl esters of the lead alkenyldiarylmethanes (ADAMs) with stable bioisosteres, compounds bearing benzo[d]isoxazole and oxazolidine-2-one rings were designed and evaluated as a new series of potent HIV-1 non-nucleoside reverse transc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Deng, Bo-Liang, Zhao, Yujie, Hartman, Tracy L., Watson, Karen, Buckheit, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676060/
https://ncbi.nlm.nih.gov/pubmed/18952324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.09.013
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