Wordt geladen...
Crystallographic Study of a Novel Sub-Nanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 (HIV-1) Reverse Transcriptase
Two crystal structures have been solved for separate complexes of alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTI) 3 and 4 with HIV-1 reverse transcriptase (RT). The structures reveal inhibitor binding is exclusively hydrophobic in nature and the shape of the inhib...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770579/ https://ncbi.nlm.nih.gov/pubmed/19775161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901167t |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|