Structure of the Disordered C Terminus of Rab7 GTPase Induced by Binding to the Rab Geranylgeranyl Transferase Catalytic Complex Reveals the Mechanism of Rab Prenylation

Protein prenylation is a widespread process that involves the transfer of either a farnesyl or a geranylgeranyl moiety to one or more C-terminal cysteines of the target protein. Rab geranylgeranyl transferase (RabGGTase) is responsible for the largest number of individual protein prenylation events...

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Hlavní autoři: Wu, Yao-Wen, Goody, Roger S., Abagyan, Ruben, Alexandrov, Kirill
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Membrane Transport, Structure, Function, and Biogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676050/
https://ncbi.nlm.nih.gov/pubmed/19240028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900579200
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